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Flu vaccine won't prevent second heart attack

Results of a two-year study involving 1,300 heart attack victims was published recently in the American Journal of Epidemiology. Contradicting prior claims that a flu shot might lower the risk of a second heart attack, the study showed that receiving the influenza vaccination reduced neither the likelihood of a second attack nor dying due to heart disease.

"These results suggest that the benefit of influenza vaccine for older adults does not extend to protection against recurrent coronary events," the study's authors concluded.

"Although our results do not suggest a benefit of influenza vaccine in the prevention of recurrent coronary events, the benefits of the vaccine in preventing serious complications of influenza infection are well documented," they wrote.

Yet, they failed to mention the potential side effects of the vaccine, which include fever, fatigue, painful joints and headache. The most severe reaction is Guillain-Barré Syndrome (GBS), a rare but serious adverse reaction that can occur in two to four weeks of a vaccination. This syndrome is a nerve disorder characterized by muscle weakness, unsteady gait, numbness, tingling, pain and, sometimes, paralysis to one or more limbs or to the face.

According to the National Vaccine Information Center (NVIC), the flu vaccine is prepared from the fluids of chick embryos inoculated with a specific type (or types) of influenza virus. The strains of flu virus in the vaccine are inactivated with formaldehyde and preserved with thimerosal, which is a mercury derivative.

"Every year, federal health agency officials try to guess which three flu strains are most likely to be prevalent in the U.S. the following year to determine which strains will be included in next year's flu vaccine," the NVIC explained. "If they guess right, the vaccine is thought to be 70-80% effective in temporarily preventing the flu of the season in healthy persons less than 65 years old (the efficacy rate drops to 30-40% in those over 65 years old but the vaccine is thought to be 50-60% effective in preventing hospitalization and pneumonia and 80% effective in preventing death from the flu in the over 65 age group). However, sometimes health officials do not correctly predict which flu strains will be most prevalent and the vaccine's effectiveness is much lower for that year."

Although rarely mentioned by medical doctors when giving the shot, the Centers for Disease Control (CDC) and the vaccine manufacturers list recipients whose at-risk conditions should be noted before the vaccine is administered. These include anyone sick with a fever, or who has an impaired immune system, an egg or mercury allergy, or a history of GBS.

In years past, pregnancy was also a contraindication to flu vaccine but, today, the CDC's Advisory Committee on Immunization Practices recommends flu vaccine for women more than 14 weeks pregnant.

Still, the NVIC warns that pregnant women should be aware that the flu vaccine contains thimerosal, which is a mercury derivative. Mercury is toxic to the brain and has been found to be associated with brain damage and developmental delays in babies whose mothers were exposed to high levels of mercury during pregnancy.

SOURCES: "Influenza Vaccination Is Not Associated with a Reduction in the Risk of Recurrent Coronary Events," by Lisa A. Jackson, et al, American Journal of Epidemiology, October 1, 2002.

"The flu and the flu vaccine," National Vaccine Information Center.

 

 

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